Alternative in vitro methods to characterize the role of Endocrine Active Substances (EASs) in hormone-targeted tissues.
نویسندگان
چکیده
to some authors, eASs are supposed to challenge the canonical paradigms of toxicology, e.g., linear versus non-monotonic dose response, low dose effects versus threshold concept. An overview of the symposium is given here; authorized presentations and the abstract book are available on the websites of the three organizing institutes, i.e., ISS (http://www.iss.it/inte/ prog/cont.php?id=263&lang=2&tipo=10); IPAM (http://www. ipamitalia.it), and CAAt (http://caat.jhsph.edu/media/slides/ed/ index.html).
منابع مشابه
Topic 4.11 Effects of endocrine active substances in wildlife species: Genetic, biochemical, and physiological factors in variable susceptibility to endocrine disruptors*
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There have been several case studies of the impact of chemical contaminants on birds at the level of individuals or populations. While many of the chemicals involved in these incidents have been classified as endocrine-disrupting chemicals or endocrine active substances (EASs) the mechanisms by which these chemicals affect birds are not clearly or fully understood.
متن کاملAN ENVIRONMENTALIST’S PERSPECTIVE OF RISKS OF ENDOCRINE ACTIVE SUBSTANCES (EASs) TO WILDLIFE
This paper reviews the existing concerns and presents conclusions and recommendations for action. The first section outlines an environmentalist’s perspective and predicts that endocrine active substances (EASs) pose a high risk for wildlife populations. The second section explains that risk assessment, as currently practiced for individual chemicals, does not adequately protect the environment...
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ورودعنوان ژورنال:
- ALTEX
دوره 30 2 شماره
صفحات -
تاریخ انتشار 2013